Yesterday we reported that metabolic syndrome, which is closely associated with PCOS, may be an indicator of breast cancer risk in post-menopausal women, according to new research.
A study analyzed 777 patients and found a higher prevalence of metabolic syndrome symptoms among post-menopausal women with breast cancer (33%) when compared to post-menopausal women without breast cancer (19%).
In the age range of 55 to 65 years, 40% of the breast cancer cases had more than three metabolic syndrome features, which can range from insulin resistance and high blood pressure to excess weight gain and high levels LDL “bad” cholesterol and triglyceride body fats.
The study showed that while none of the individual features of metabolic syndrome was strong enough to be considered responsible for the onset of breast cancer, researchers hypothesized that the unsettling of the hormonal arrangement in postmenopausal women, along with an increase in weight gain, particularly around the central portion of the body, may favor hormone-dependent cell proliferation. The latter drives the inception of tumors.
“These findings might have important clinical implications because they could be the basis for a breast cancer prevention strategy based on adjustments in lifestyle with physical activity intensification and a healthy diet,” said the study, which was based primarily on research by an Italian cancer center.