LABS-2: Preoperative reproductive concerns prevalent in certain bariatric patients

Endocrine Today

By Eric Raible
June 25, 2008

Women with obesity who desire bariatric surgery often present with reproductive complications prior to surgery, results from a prospective study suggested.

Researchers with the six-center Longitudinal Assessment for Bariatric Surgery II (LABS-2) study reported that reproductive disorders like polycystic ovary syndrome, abnormal bleeding and menstrual cycles, and infertility were prevalent in the study cohort of obese women prior to undergoing bariatric surgery.

The researchers provided a self-administered 20-item reproductive health questionnaire to 1,024 women, according to Gabriella G. Gosman, MD, assistant professor of medicine at the University of Pittsburgh School of Medicine. She presented the results at the 25th Annual Meeting of the American Society for Metabolic and Bariatric Surgery in Washington.

“Among women presenting for bariatric surgery, there was a high prevalence of PCOS and abnormal menstrual function,” Gosman said. “Both of these have serious health consequences, including endometrial cancer.”

Gosman reported a higher prevalence of PCOS in the cohort compared with that of the general population (15.9% vs. 7%), as well as abnormal menses (32.2% vs. 18%). About 45% of the women in the cohort were reported as using estrogen-based contraceptives in the year leading up to bariatric surgery.

“We propose that clinicians determine whether future pregnancy is desired, and stratify women get counseling and care for the interaction between bariatric surgery and pregnancy, or for long-term reliable contraception,” she said. “Regardless of future pregnancy plans, all of these women would need reliable contraception from the decision to undergo surgery until the time that rapid weight loss has ceased.”


We are excited that the LABS data are starting to come out. I am concerned about the validation of this questionnaire. For it to be a reliable research tool, any questionnaire has to be validated. We have to be confident that it accurately measures what it is expected to measure in different populations and in different ways by different people. To draw data from it unless it has been validated and each component has been validated leaves us feeling uncertain of what we are looking at.

– Paul E. O’Brien, MD, Director, Center for Obesity & Education Monash University, South Yarra, Australia

    For more information:

        * Gosman G. #PL 39. Reproductive health characteristics of women undergoing bariatric surgery. Presented at: the American Society for Metabolic and Bariatric Surgery’s Annual Scientific Meeting; June 15-20, 2008; Washington D.C.


Next Steps

Becoming victorious over the symptoms of Polycystic Ovary Syndrome is not easy, but you can overcome your PCOS symptoms to live the life you deserve.

It takes strength, courage, and perseverance. It can be challenging and that’s why Insulite Health created this website. It's has information and resources that will help you balance your hormones and reverse PCOS symptoms.

So take these next steps now! Use the links below to learn how to make the changes that will transform your health and your life forever.

  1. Read more about PCOS. Search our 1300 page PCOS library.
  2. Join our Facebook Group right now!  Pose your questions to this group of like-minded women and get the support you need.
  3. Take the PCOS Quiz! Get your PCOS score and assess your risk.  
  4. Learn more about the Insulite 5-Element PCOS Solution

Insulite Health, is committed to helping women reverse their symptoms of hormone imbalance. Scientific research has revealed that this imbalance can be a primary cause of many devastating health symptoms. Hormone Imbalance can also underlie the increased risk factors for PCOS (Polycystic Ovarian Syndrome) - a major source of serious diseases as well as cause of excess weight gain, adult acne, unwanted facial hair, depression, anxiety, and heartbreaking female infertility.

©Insulite Health, Inc., empowers women with PCOS to transform their lives through a process of healing with the 5-Element PCOS System – a complete solution for helping women reverse the symptoms of PCOS and hormone imbalance.