Polycystic Ovary Syndrome and Migraine Headache, Is There Any Correlation?

S. Pourabolghasema, S. Najmib, M.A. Aramic

Department of Obstetrics and Gynecology, Tabriz University (Medical Sciences), Taleghani Hospital,
Consultant Neurologist, Tabriz University (Medical Sciences), Razi Hospital, Tabriz,
Consultant Neurologist, Neurology Clinic, Milad General Hospital, Tehran, Iran

Eur Neurol 2009;61:42-45 (DOI: 10.1159/000165349)

Abstract

Background: To evaluate the role of some sex hormones in migraine headaches, the aim of this study was to assess the prevalence and characteristics of headache, especially migraine, in patients with polycystic ovary syndrome (PCO) compared with women without this disease. Methods: One hundred and thirty-three women with PCO and 107 controls were interviewed by 2 neurologists experienced in headache diagnosis. The headache disorders were classified according to the International Headache Society criteria. The statistical significance was determined using the chi2 test, and a p value of <0.05 was considered significant. Results: Forty-five women (33.8%) of the 133 cases without PCO complained of headache. Of the PCO patients, 48 women (44.9%) suffered from headache. The prevalence of headache was not significantly higher among women with PCO (p = 0.85). The same results were found for migraine headache (p = 0.13). Conclusion: Migraine is not more frequent in women with PCO. It was concluded that male sex hormones and especially testosterone do not play an important role in the exacerbation of migraine headache.

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